Tight sandstone reservoir of Jurassic Ahe Formation in Kuqa depression (Tarim Basin, NW China) has strong heterogeneity, therefore, the prediction of sweet spots is important for natural gas exploration in this area. Based on the collected cores, well logging and seismic data, the detailed analysis of the reservoir space characteristics and origins in the Ahe Formation, the sand body architecture analysis and fractures analysis are carried out to predict the sweet spots. The results of petrologic study shows that the reservoir space of lithic sandstone in the Ahe Formation are intragranular dissolved pores and micro pores, and the area where pores are communicated by effective fractures is easy to form effective reservoir sweet spots. The favorable reservoirs of the Ahe Formation are developed in four types of sand body including progradational bar sandstone, lateral bar sandstone, lag deposits and overflow sand within floodplain. And three types of sweet spots can be predicted by the combination of the sand body and fractures. We believe this research is of great significance to the prediction of sweet spots of tight reservoirs in other foreland basins.