The mineralogical composition of the mine waste dumps influence the chemical composition of the products resulted from the specific weathering reactions of the metallic and gangue minerals. The geochemistry characteristics of the mine waste dump influence natural installation of the plants species. The chemical analysis of the material and of the natural vegetation from the mine waste dumps emphasizes the high concentrations of: Pb, Cu, Zn, and Mn. The plants which adapted to the particular conditions of the different zones in the studied mining sites can be used as vegetable material for the mining waste rehabilitation. The study of the flora from the old mine waste dumps offers information about the chemistry of the substratum which favoured the installation of the vegetation and about the plants species associations.